A single control center for sleep and wake in the brain Until now, it was thought that multiple brain areas were needed to control sleep and wakefulness. Neuroscientists from Bern have now identified one single control center for the sleep-wake cycle in the brain. The findings are of great importance for finding new sleep therapies.
- The Stony Brook Medicine Sleep Disorders Center was named to Sleep Review's Best of 2013 Sleep Doctors and Facilities list. The center is the only New York facility named to the list compiled by the national professional journal for sleep specialists and was chosen based on the recommendation of a national panel of leading sleep professionals.
- UPMC Pinnacle Sleep Medicine - Alexander Spring 1533 Commerce Avenue Suite 2 Carlisle, PA 17015 Phone: 717-791-2520 Fax: 717-920-4361.
- Dec 06, 2015 My Windows 10 PC will enter sleep mode regardless of the power settings. I have set it to never sleep. After a reboot, it stays awake for quite a while, up to several hours, but then it will go to sleep. After it has gone to sleep the first time it will do it more and more often, and after a while it stays awake only 2-3 minutes when idle.
There are many ways to shut down your PC—you can turn the PC off completely, you can make it sleep, or you can hibernate the PC.
Turn your PC off completely
To shut down:
For Windows 10 | Select Start and then select Power > Shut down. |
For Windows 8.1 / Windows RT 8.1 | Move your mouse to the lower left-hand corner of the screen and right-click the Start button or press Windows logo key + X on your keyboard. Tap or click Shut down or sign out and choose Shut down. |
For Windows 7 | Click the Start button and then click the Shut down button. |
Sleep
This uses very little power, your PC starts up faster, and you’re instantly back to where you left off. You don’t have to worry that you'll lose your work because of your battery draining, because Windows automatically saves all your work and turns off the PC if the battery is too low. Use sleep when you’re going to be away from your PC for just a little while—like when you’re taking a coffee break.
For a lot of PCs (especially laptops and tablets), your PC goes to sleep when you close your lid or press the power button.
To make your PC sleep:
Open power options:
For Windows 10, select Start, then select Settings > System > Power & sleep > Additional power settings.
For Windows 8.1 / Windows RT 8.1, swipe in from the edge of the screen, tap Search (or if you're using a mouse, point to the upper-right corner of the screen, move the mouse pointer down, and then click Search), enter Power options in the search box, and then tap or click Power options.
For Windows 7, click the Startbutton , click Control Panel, click System and Security, and then click Power Options.
Do one of the following:
If you’re using a desktop, tablet, or laptop, select Choose what the power buttons do. Next to When I press the power button, select Sleep, and then select Save changes.
If you’re using only a laptop, select Choose what closing the lid does. Next to When I close the lid, select Sleep, and then select Save changes.
When you’re ready to make your PC sleep, just press the power button on your desktop, tablet, or laptop, or close your laptop’s lid.
On most PCs, you can resume working by pressing your PC's power button. However, not all PCs are the same. You might be able to wake it by pressing any key on the keyboard, clicking a mouse button, or opening the lid on a laptop. Check the documentation that came with your computer or go to the manufacturer's website.
Hibernate
This option was designed for laptops and might not be available for all PCs. (For example, PCs with InstantGo don't have the hibernate option.) Hibernate uses less power than sleep and when you start up the PC again, you’re back to where you left off (though not as fast as sleep).
Use hibernation when you know that you won't use your laptop or tablet for an extended period and won't have an opportunity to charge the battery during that time. First check to see if this option is available on your PC and if it is, turn it on.
To hibernate your PC:
Open power options:
For Windows 10, select Start, then select Settings > System > Power & sleep > Additional power settings.
For Windows 8.1 / Windows RT 8.1, swipe in from the edge of the screen, tap Search (or if you're using a mouse, point to the upper-right corner of the screen, move the mouse pointer down, and then click Search), enter Power options in the search box, and then tap or click Power options.
For Windows 7, click the Start button , click Control Panel, click System and Security, and then click Power Options.
Select Choose what the power button does, and then select Change settings that are currently unavailable. Under Shutdown settings, select the Hibernate checkbox (if it's available), and then select Save changes.
Now you’ll be able to hibernate your PC in a few different ways:
For Windows 10, select Start , and then select Power > Hibernate. You can also press the Windows logo key + X on your keyboard, and then select Shut down or sign out > Hibernate.
For Windows 8.1 / Windows RT 8.1, move your mouse to the lower left-hand corner of the screen and right-click the Start button or press Windows logo key + X on your keyboard. Tap or click Shut down or sign out and choose Hibernate. Or, swipe in from the right edge of the screen and then tap Settings. (If you're using a mouse, point to the lower-right corner of the screen, move the mouse pointer up, and then click Settings.) Tap or click Power > Hibernate.
For Windows 7, click the Start button , click the arrow next to the Shut down button, and then click Hibernate.
Note: If devices connected to your PC (like monitors, printers, or scanners) aren't working properly after waking up from sleep or hibernate, you might need to disconnect and reconnect your device or restart your PC. You should also make sure that you have the most current drivers for all of your devices.
Sleep Number Firmness Control Center
Research Highlights
Sleep Control Center San Jose
Novel mechanism of sleep-wake control.
PI/Investigator: Nebojsa Kezunovic, graduate student; E. Garcia-Rill, COBRE PI.
Institution: Center for Translational Neuroscience (COBRE), Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR
Background: When we are awake with our eyes closed, electrodes on the scalp measure waves of human brain activity at 10 Hertz, or 10 per second. If we fall asleep, these waves slow to 6-8 Hertz during drowsiness and light sleep, and then to 2-4 Hertz in deep sleep. When we open our eyes, are alerted and pay attention, our brains begin to fire at 20-40 Hertz. These waves are called “gamma band activity”, and are present during consciousness and learning, and also during dreaming. Dogma was that “gamma band activity” was only present in the cerebral cortex. Recently, investigators found “gamma band activity” in other parts of the brain, such as the hippocampus and cerebellum.
Advance: Studies at the Center for Translational Neuroscience at UAMS have discovered that parts of the reticular activating system (RAS), the part of the brain that controls sleep, dreaming and waking, exhibit “gamma band activity”. In fact, nerve cells in this area prefer to fire at ~40 Hertz when stimulated. This means that the RAS activates the rest of the brain when we are alerted, and it does so, not by triggering such activity in other regions, but by itself inducing “gamma band activity”. This process thus recruits waking or dreaming. We identified the mechanism of action as the presence of voltage-dependent calcium channels (P/Q-type) that lead to these rapid oscillations.
Support: Core Facilities provided by COBRE award P20 GM104325.
Public Health Impact: This novel mechanism suggests that the RAS is more about “waking” than it is about “sleep”. Now that we know that these channels mediate high frequency oscillations, the development of new anesthetics (to block these channels) and stimulants (to activate these channels) is not far behind.
Citation and links:
Kezunovic, N., Urbano, F.J., Simon, C., Hyde, J., Smith, K., and Garcia-Rill, E. Mechanism behind gamma band activity in the pedunculopontine nucleus (PPN). Eur J Neurosci 34: 404-415, 2011. PMID: 21722210, PMCID requested.